Skip to main content

General medical information

Wrinkle

A wrinkle is a general term for a line or fold that may be visible during facial movement or at rest. Assessment requires movement, skin characteristics and individual factors to be considered together.

This translation has no recorded clinical or medical-language review. Turkish is the current indexing language.

Scope of the glossary

Definitions are for general information; they are not diagnosis, personal risk assessment or treatment advice. Source lists are editorial starting points and are not clinical-review records. Personal suitability requires an in-person physician assessment.

Related sources

These sources are editorial starting points selected to examine the scope and limitations of the procedure topic connected with this term.

  1. Microneedling for Facial Rejuvenation: A Systematic Review

    Foppiani JA et al. · 2025

    Editorial source — not a clinical-review record

  2. Evaluating the Effectiveness and Safety of Radiofrequency for Face and Neck Rejuvenation: A Systematic Review

    Austin GK, Struble SL, Quatela VC · 2022

    Editorial source — not a clinical-review record

  3. A Systematic Review and Meta-Analysis of the Clinical Efficacy and Patients' Satisfaction of Micro-Focused Ultrasound Treatment for Facial Rejuvenation and Tightening

    Ling J, Zhao H · 2023

    Editorial source — not a clinical-review record

  4. Potential Risks with Certain Uses of Radiofrequency (RF) Microneedling – FDA Safety Communication

    U.S. Food and Drug Administration (FDA) · 2025

    Editorial source — not a clinical-review record